Pagliarini Lab
Pagliarini Lab
  • Home
  • Research
    • Overview
    • Systems Biochemistry
    • CoQ Biosynthesis
    • Mitochondrial Regulation
  • Publications
    • Featured
    • All by year
  • News
  • Meet Our Team
    • Dave Pagliarini
    • Current Lab
    • Lab Alumni
  • Contact
  • More
    • Home
    • Research
      • Overview
      • Systems Biochemistry
      • CoQ Biosynthesis
      • Mitochondrial Regulation
    • Publications
      • Featured
      • All by year
    • News
    • Meet Our Team
      • Dave Pagliarini
      • Current Lab
      • Lab Alumni
    • Contact
  • Home
  • Research
    • Overview
    • Systems Biochemistry
    • CoQ Biosynthesis
    • Mitochondrial Regulation
  • Publications
    • Featured
    • All by year
  • News
  • Meet Our Team
    • Dave Pagliarini
    • Current Lab
    • Lab Alumni
  • Contact
data:image/gif;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=

Welcome to the Pagliarini Lab

We are an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation, and basic metabolic function of mitochondria.

Join our team

Recent Discoveries

New function of IM protein in CoQ biosynthesis

A role for TAGs in mitochondrial stress recovery

New function of IM protein in CoQ biosynthesis

Baker et al.,
Nature Communications 2026

New enzymes in hydroxy-lipid metabolism

A role for TAGs in mitochondrial stress recovery

New function of IM protein in CoQ biosynthesis

Rashan et al., NSMB 2025

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

Baker et al., Nature Cell Biology, 2025

An unexpected role for NDUFAF6 in CI Assembly

A new isoprene transporter for CoQ biosynthesis

A role for TAGs in mitochondrial stress recovery

Sung et al., Nature Metabolism, 2024

A new isoprene transporter for CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

Tai et al., Nature Cell Biology, 2023

A novel inhibitor of CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

A new isoprene transporter for CoQ biosynthesis

Murrary et al., Nature Chem Bio, 2023

Explore our research

Meet the team

View recent news

2025 Pagliarini Lab

Powered by