Pagliarini Lab
Pagliarini Lab
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    • Overview
    • Systems Biochemistry
    • CoQ Biosynthesis
    • Mitochondrial Regulation
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    • Dave Pagliarini
    • Current Lab
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  • More
    • Home
    • Research
      • Overview
      • Systems Biochemistry
      • CoQ Biosynthesis
      • Mitochondrial Regulation
    • Publications
      • Featured
      • All by year
    • News
    • Meet Our Team
      • Dave Pagliarini
      • Current Lab
      • Lab Alumni
    • Contact
  • Home
  • Research
    • Overview
    • Systems Biochemistry
    • CoQ Biosynthesis
    • Mitochondrial Regulation
  • Publications
    • Featured
    • All by year
  • News
  • Meet Our Team
    • Dave Pagliarini
    • Current Lab
    • Lab Alumni
  • Contact
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Welcome to the Pagliarini Lab

We are an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation, and basic metabolic function of mitochondria.

Join our team

Recent Discoveries

Phosphorylation shapes mitochondrial functions

Phosphorylation shapes mitochondrial functions

Phosphorylation shapes mitochondrial functions

Smith et al.,
bioRxiv 2026

New function of IM protein in CoQ biosynthesis

Phosphorylation shapes mitochondrial functions

Phosphorylation shapes mitochondrial functions

Baker et al.,
Nature Communications 2026

New enzymes in hydroxy-lipid metabolism

Phosphorylation shapes mitochondrial functions

A role for TAGs in mitochondrial stress recovery

Rashan et al., NSMB 2025

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

A role for TAGs in mitochondrial stress recovery

Baker et al., Nature Cell Biology, 2025

An unexpected role for NDUFAF6 in CI Assembly

A role for TAGs in mitochondrial stress recovery

A new isoprene transporter for CoQ biosynthesis

Sung et al., Nature Metabolism, 2024

A new isoprene transporter for CoQ biosynthesis

A role for TAGs in mitochondrial stress recovery

A new isoprene transporter for CoQ biosynthesis

Tai et al., Nature Cell Biology, 2023

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Meet the team

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2025 Pagliarini Lab

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